Pain after cesarean section
Conditions
Interventions
Ultrasound guided bilateral LB-AQLB group (group A):After surgery, ultrasound guided bilateral LB-AQLB was performed by an experienced anesthesiologist
LB-QLB-LSAL group (group L):After surgery, ultrasound guided bilateral LB-QLB-LSAL was performed by an experienced anesthesiologist
Sponsors
Anhui Women and Children Medical Center
Eligibility
Sex/Gender
Female
Age
20 Years to 36 Years
Inclusion criteria
Inclusion criteria: (1) term 37-41 gestational weeks (2) singleton pregnancy (3) age 20-36 years old (4) BMI 21.0-35.0 kg/m^2 (5) ASA grade II or III
Exclusion criteria
Exclusion criteria: (1) any related major cardiac or respiratory disease, hematological system disease or coagulation parameter disorder, pre-existing vital organ dysfunction (such as liver and kidney failure). (2) contraindications of neuraxial anesthesia and nerve block. (3) severe pregnancy complications (high-risk pregnancy such as severe preeclampsia, placental abruption and complete placenta previa). (4) known fetal abnormalities. (5) history of chronic pain. (6) patients with mental disorders or inability to understand NRS scores. (7) patients allergic to opioid or liposomal bupivacaine. (8) patients who refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| 0-72 h pain Numerical rating scale (NRS) area under curve (AUC);NRS after surgery;MAP and HR were measured after surgery;Patient comfort score (BCS);Quality of recovery score (QoR-15 scale);Plasma interleukin-6 (IL-6) levels;Tumor necrosis factor-a (TNF-a) levels; | — |
Countries
China
Contacts
Public ContactTianzhen Ji
Anhui Women and Children Medical Center
Outcome results
None listed