Atopic dermatitis
Conditions
Interventions
Probiotics group:Administer pediatric-formulated microencapsulated dry powder probiotics to the study subjects, once daily, one sachet per dose.
Probiotics + prebiotics group:Administer soluble dietary fiber (5g per sachet) and pediatric-formulated microencapsulated dry powder probiotics (1 sachet) to the study subjects
both the prebiotics and probiotics should be taken dissolved in lukewarm water.
Sponsors
Shanghai Fifth People's Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
No minimum to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 0–6 years, 2. Diagnosed with atopic dermatitis meeting mild criteria, with a SCORAD score classified as mild (score 0–24 points), 3. Voluntary participants.
Exclusion criteria
Exclusion criteria: 1. Four types of allergic diseases classified as moderate to severe, 2. History of severe allergic reactions or anaphylactic shock, 3. Within 1 week of vaccination, 4. Acute skin infection, 5. Presence of other severe diseases, 6. Systemic corticosteroid therapy, 7. Use of probiotics, prebiotics, or antibiotics within 6 weeks prior to study inclusion, 8. Unwillingness to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCORAD;Children's Dermatology Life Quality Index, cDLQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemical indicators;Gut microbiota; | — |
Countries
China
Contacts
Public ContactShao Chunhai
Shanghai Fifth People's Hospital, Fudan University
Outcome results
None listed