Perioperative Neurocognitive Dysfunction
Conditions
Interventions
Intervention group:Oral administration of sodium phosphate solution is scheduled between 12:00 and 16:00
Control group:Oral administration of sodium phosphate solution is scheduled between 18:00 and 22:00
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1 Patients with primary colorectal cancer 2 Patients scheduled for elective colorectal cancer resection surgery and requiring mechanical bowel preparation 3 Age >= 18 years 4 American Society of Anesthesiologists grade =? 5 Understand and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1 People taking long-term (continuous or intermittent) medication such as benzodiazepine sleeping pills, antidepressants or tranquilizers that can affect cognitive function 2 Mini-mental state examination (MMSE) scores: illiterate =17, elementary school =20, secondary school or above =24 3 History of psychotic disorders, organic encephalopathy, or other neurodegenerative diseases 4 Impaired vision or hearing that prevents assessment of cognitive functioning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative cognitive dysfunction;Quality of sleep the night before surgery;electrolyte concentration;Postoperative pain score;Postoperative complications and mortality rates;Demographic and surgical profles of the patients; | — |
Countries
China
Contacts
Public ContactJing Shi
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed