early cervical pancreatic cancer
Conditions
Interventions
Observation group:Central pancreatectomy
Control group:traditional pancreatic body and tail combined with splenectomy
Sponsors
The Affiliated BenQ Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-80 years old;2.According to clinical symptoms, imaging examination, tumor markers and other auxiliary examinations before surgery and postoperative pathology, it was determined that the tumor size was <= 2 cm, the tumor was located in the neck or tail of the pancreas, and the tumor was enhanced without lymph nodes or distant metastasis, and the diagnosis was early T1 stage pancreatic neck cancer or pancreatic body and tail cancer; 3. No surgical contraindications, able to tolerate radical surgery;4. Compliance with the study plan and follow-up procedure; 5. Obtain informed consent signed by the patient or his or her legal agent.
Exclusion criteria
Exclusion criteria: 1. Malignant tumors in other areas within the last 5 years; Patients with brain, lung, bone metastases or abdominal lymph node metastases; 2. patients with severe cardiopulmonary function, liver and renal function infection; 3. Infection of HCV, HIV, syphilis; 4. Women during pregnancy or lactation.5.Patients who required pancreaticoduodenectomy or total pancreatectomy before surgery based on clinical symptoms, imaging examination, tumor markers and other auxiliary examinations; 6.Prior pancreaticoduodenectomy was performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor R0 resection rate;The incidence of short-term postoperative complications;Recurrence-free survival time;Overall survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin A1c level;The usage of oral hypoglycemic drugs and insulin after the operation;Hospitalization expenses;Postoperative hospital stay days; | — |
Countries
China
Contacts
Public ContactYi Miao
Nanjing Medical Affiliated BenQ Hospital University
Outcome results
None listed