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Effectiveness of High-intensity Interval Training on the Patients with Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia or Obesity: A Randomized Controlled Trial

Effectiveness of High-intensity Interval Training on the Patients with Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia or Obesity: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102061
Enrollment
Unknown
Registered
2025-05-08
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension, hyperglycemia, hyperlipidemia, high uric acid, obesity

Interventions

MICT group:Each MICT training is conducted 3 times per week for 12 weeks under supervision. The MICT intervention consisted of 2 × 16-minute continuous aerobic training phases at an intensity of 40-70
HIIT group:HIIT will be done thrice a week on a cycle ergometer under supervision at the research facility for 12 weeks. Each HIIT exercise session consisted of two 8-minute training sessions, totalin
Control group:Participants in this group did not undergo the exercise intervention, but continued their normal daily routines and activities.

Sponsors

Shanghai University of Medicine and Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Subjects aged 20 years old or more; 2. Participants who meet one of the diagnostic criteria for hypertension, hyperglycemia, hyperlipidemia, hyperuric acid, or obesity; 3. Be willing to participate and have signed an informed consent form; 4. Be in a stable chronic disease state; 5. Have not participate in regular moderate-intensity physical activities (at least 3 times a week, with lasting at least 30 minutes a day).

Exclusion criteria

Exclusion criteria: 1. Unstable angina pectoris, history of cerebrovascular accident, malignant hypertension, myocardial infarction, heart failure, diabetic ketoacidosis, and other critical illnesses within the last six months; 2. Those with other major chronic diseases, such as chronic kidney disease, systemic lupus erythematosus, chronic hepatitis, hypothyroidism, etc. resulting in abnormal weight and blood glucose; 3. Patients with unstable conditions, such as those with resting systolic blood pressure >200 mmHg or diastolic blood pressure >110 mmHg, uncontrolled peripheral vascular disease or recent frequent hypoglycemic events (<=4 mmol/L); 4. Patients with cancer, acute infections, psychiatric disorders, severe motor system abnormalities, etc. are not suitable for those who receive interventions from this program; 5. Other metabolic abnormalities such as acute thyroiditis, hypokalemia, hyperkalemia, or hypovolemia; 6. Patients with infectious diseases within the last month; 7. People with severe osteoporosis who are unable to tolerate exercise, people with chronic heavy drinking habits and those who are unable to maintain a routine during the intervention period; 8. Those who did not accept the management of the program, could not guarantee that they would follow the prescribed exercise regimen during the intervention, and did not sign the informed consent; 9. Participants who are taking part in other trials that may affect the results of this study.

Design outcomes

Primary

MeasureTime frame
Fasting blood glucose (FBG);HbA1c;Insulin;Blood pressure;Weight;Height;Waist circumference;Blood lipid;Uric acid;

Secondary

MeasureTime frame
Heart rate;Bone mineral density;Body composition;Maximal oxygen uptake;Grip strength;Walk speed;TUGT;SPPB;Anxiety;Depression;Life quality ;Sleep;

Countries

China

Contacts

Public ContactQi Guo

Shanghai University of Medicine and Health Sciences

guoqijp@gmail.com+86 131 6253 7578

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026