Acute kidney injury
Conditions
Interventions
remote ischemic preconditioning group:Before the contrast-enhanced CT scan, a blood pressure cuff will be applied to one upper arm and inflated to 50 mmHg for 5 minutes, followed by release to 0 mmHg
control group:In the control group, the sphygmomanometer cuff was also placed on the single-sided upper arm of the patient, but no pressure was applied to the cuff. This process lasted for 40 minutes,
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years; 2. Scheduled to undergo enhanced CT examination; 3. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of AKI (Acute Kidney Injury) at admission or prior to the current CT examination; 2. Intravascular administration of iodinated contrast media within the past 7 days; 3. Diagnosis of end-stage renal disease (ESRD) prior to or at admission, or receiving maintenance hemodialysis/peritoneal dialysis/renal transplantation, or baseline estimated glomerular filtration rate (eGFR) <15 mL/min/1.73m²; 4. Undergoing emergency CT; 5. Presence of conditions deemed by medical personnel as unsuitable for upper arm cuff compression or other circumstances that make participation in the study inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Contrast-Induced Acute Kidney Injury (CI-AKI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Require renal replacement therapy ;Develop Acute Kidney Disease (AKD) ;Develop Chronic Kidney Disease (CKD);Be transferred to the Intensive Care Unit (ICU);Death;Develop major adverse kidney events (MAKEs) within 120 days after discharge from the hospital ; | — |
Countries
China
Contacts
Public ContactYuliang Zhao
West China Hospital, Sichuan University
Outcome results
None listed