chronic graft-versus-host disease
Conditions
Interventions
Gold Standard:The diagnostic criteria of chronic graft-versus-host disease refer to the Chinese expert consensus on the diagnosis and treatment of chronic graft-versus-host disease (2024).
Index test:Prediction model of chronic graft-versus-host disease
Sponsors
The Second Affiliated Hospital of Army Medical University (Xinqiao Hospital of Army Medical University )
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (a) Age >= 18 years old, <=70 years old, both male and female; A suitable donor for allogeneic transplantation; (b) The underlying disease was stable, no progression and no recurrence; (c) Patients or guardians who are willing and able to provide informed consent; (d) Women with reproductive potential are willing to use contraception; (e) Willingness to comply with research programmes and research requirements.
Exclusion criteria
Exclusion criteria: (a) Progression or recurrence of underlying diseases; (b) Complicated with other malignant tumors and undergoing treatment; (c) Infusion of donor lymphocytes or Car-T cells within the last 30 days; (d) Active infection, invasive fungal or viral infection, ineffective against fungal or antiviral therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specific biomarkers ( including : chemokine family, interleukin family, cell subsets, etc. ); | — |
Countries
China
Contacts
Public ContactZhang Xi
Medical Center of Hematology, Xinqiao Hospital of Army Medical University
Outcome results
None listed