radiation pneumonitis
Conditions
Interventions
Retrospective cohort:None
Prospective cohort:None
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1. Age >= 18 years, histologically confirmed primary lung cancer (including adenocarcinoma, squamous cell carcinoma, small-cell lung cancer, or other subtypes). 2. No prior thoracic surgery or other treatments affecting the chest region. 3. Eastern Cooperative Oncology Group (ECOG) performance status = 3 months. 4. Availability of chest CT scans at approximately 1 month, 3 months, and 6 months (+- 15 days) after completion of radiotherapy for imaging-based assessment of lung changes. 5. Fully informed about the study, willing to participate, able to comply with treatment and follow-up procedures, and has provided written informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria 1. Interruption of radiotherapy for more than one week or inability to complete the prescribed radiotherapy course. 2. Incomplete imaging data or inability to perform follow-up assessments. 3. Pre-existing severe pulmonary disease (e.g., severe COPD, interstitial lung disease) that would confound risk assessment for radiation pneumonitis. 4. Participant withdrawal of informed consent. 5. Other circumstances deemed by the investigator to warrant discontinuation from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of radiation pneumonitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Independent contributions of radiomics, digital pathology, and dosimetric features to the prediction of radiation pneumonitis.;OS,PFS,DFS; | — |
Countries
China
Contacts
Public ContactZhengzhou Yang
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed