Photoaging
Conditions
Interventions
Monopolar Radiofrequency treatment group:Monopolar Radiofrequency therapy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Age range: 30-50 years old, and the gender was not limited; (2) Fitzpatrick Wrinkle Classification Scale (FWCS) score for facial wrinkles was 3~5 . (3) Subjects voluntarily participated in this study, came to the hospital for treatment and examination at a time arranged by the investigator, and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Subjects were excluded if they met any of the following criteria: (1) A history of severe skin sensitization and the subject is in the active phase of skin sensitization; (2) Exposure to sunlight (e.g., sunbathing or outdoor workers) within the last 1 week; (3) The area to be treated has received anti-wrinkle treatment such as botulinum toxin and fat injection within the last 6 months; (4) The area to be treated has been treated with monopolar radiofrequency or ultrasonic knife, or injected with facial fillers such as sodium hyaluronate, polylactic acid or PCL within the past 1 year; (5) Have received a face lift in the area to be treated within the last 1 year, or have undergone other facial plastic surgery; (6) Planning to undergo major facial surgery or other facial aesthetic related treatments during the study period; (7) who have received bipolar or multipolar radiofrequency-type treatment, peel laser-type treatment within the last 6 months, or other photoelectric treatment such as facial photorejuvenation within the last 3 months; (8) Those who have undergone or plan to undergo deep chemical peels during the trial within the last 1 month, or those who have used or plan to use retinoic acid or isotretinoin treatments during the trial within the last 1 month; (9) have used or plan to use antihistamines, anti-inflammatory and immunosuppressive drugs during the trial within the last 2 months; (10) Those with connective tissue disease or keloid scarring; (11) Those with autoimmune diseases (e.g., lupus erythematosus), psoriasis, vitiligo, or in the active phase of herpes simplex; (12) Those who have a combination of serious systemic diseases (e.g. diabetes mellitus, hypertension, etc. that are still uncontrollable after treatment), or serious mental illnesses; (13) Subjects with severe cardiac, hepatic, or renal dysfunction or a history of malignant tumors; (14) Inflammatory reactions, significant scarring, hemangiomas, severe acne, and other skin lesions in the area to be treated that affect the determination of test results; (15) Subjects with cancerous or pre-cancerous lesions in the area to be treated, or those who have received radiation therapy locally; (16) Those with systemic or localized infections; (17) Those with bleeding disorders; (18) Persons with an implantable pacemaker, implantable cardioverter-defibrillator (ICD), or any other type of implanted electronic device; (19) Persons with metal implants under the area to be treated, such as dental metal implants; (20) Persons who are severely obese with a BMI > 30; (21) History of facial nerve palsy; (22) Women who are pregnant or breastfeeding, or who plan to have children during the study period; (23) Conditions deemed unsuitable for this study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin thickness;Clinical grading of elasticity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Global Aesthethic Improvement Scale; | — |
Countries
China
Contacts
Public ContactXiang Wen
West China Hospital, Sichuan University
Outcome results
None listed