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The impact of individualized PEEP titration guided by driving pressure on postoperative atelectasis and cerebral oxygen saturation in patients undergoing laparoscopic surgery

The impact of individualized PEEP titration guided by driving pressure on postoperative atelectasis and cerebral oxygen saturation in patients undergoing laparoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102045
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-01-06
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

disease of respiratory system

Interventions

Drive pressure guidance PEEP titration group:None
Fixed PEEP group:None
Do not set PEEP group:None

Sponsors

Yan'an University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 50 - 80; 2. ASA classification (American Society of Anesthesiologists 2020 version) Grade I - III; 3. Body Mass Index (BMI) 18.5 - 28 kg/m²

Exclusion criteria

Exclusion criteria: 1. Previous history of cardiovascular system-related diseases; 2. Preoperative combination of severe pulmonary; 3. Preoperative SPO2 < 90%; 4. History of previous pulmonary, cardiac and thoracic surgeries, and patients with thoracic deformities; 5. Has a history of allergy to anesthetic drugs; 6. There are contraindications for radial artery catheterization

Design outcomes

Primary

MeasureTime frame
Incidence of pulmonary complications within 7 days after surgery;

Secondary

MeasureTime frame
Postoperative pulmonary ultrasound score;PACU Delirium Score;Local cerebral oxygen saturation;hemodynamics;Respiratory mechanics;blood gas;

Countries

China

Contacts

Public ContactZheng Jun

Yan'an University Affiliated Hospital

542343359@qq.com+86 138 9111 1008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026