menopausal syndrome
Conditions
Interventions
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age less than 60 years old and menopause confirmed by sex hormone level testing 2. Patients with Karnofsky performance status =80 who were unable or refused hormonal therapy 3. Clinical manifestations of menopausal syndrome lasting more than one month 4. There is no contraindication of stellate ganglion block therapy, and the stellate ganglion block therapy can be adhered to 5. Patients agreed to participate in the trial and signed an informed consent
Exclusion criteria
Exclusion criteria: 1. Had participated in other clinical trials within 4 weeks before the start of the study 2. Being receiving or requiring oral estrogen or progesterone or its analogues during the trial 3. Selective estrogen receptor modulators (e.g., tamoxifen, raloxifene) or aromatase inhibitors (e.g., mestane, exemestane) are being taken or required to be taken during the trial. 4. Sleeping pills are being taken or need to be taken during the study 5. Vitamins or neurotrophic drugs are being taken or need to be taken during the trial 6. Mental and intellectual abnormalities 7. Severe skin disease 8. Coagulation disorders 9. Cardiac disorders (i.e., Class II and above cardiac function) 10. Blood pressure: systolic blood pressure =160mmHg, diastolic blood pressure >=100mmHg 11. Significantly abnormal liver and kidney function (i.e., the index is more than twice the normal value) 12. The presence of unbearable or well-defined pain, such as trigeminal neuralgia, herpetic neuralgia 13. Local anesthetic tolerance, allergy, or discontinuation due to adverse reactions during use 14. Any acute infection 15. Recent fertility needs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kupperman rating scale;9-item Patient Health Questionnaire ;GAD-7;Pittsburgh Sleep Quality Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Karnofsky performance status score;Safety evaluation; | — |
Countries
China
Contacts
Public ContactLin Fuqing
Shanghai Tenth People's Hospital
Outcome results
None listed