stomach cancer/esophageal cancer/lung cancer?
Conditions
Interventions
test group 1(Gastric/esophageal cancer patients):Oral administration of Snow Lotus Stem Cell Small Molecule Peptides
test group 2(Lung cancer patients):Oral administration of Snow Lotus Stem Cell Small Molecule Peptides
placebo group(10 patients with Gastric/esophageal cancer patients , 10 patients with Lung cancer patient):placebo
Sponsors
Hefei Cancer Hospital,Chinese Academy of Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Aged 18 years or older, regardless of gender; (2) Patients with lung cancer and gastric/esophageal cancer confirmed cytologically or histologically; (3) TNM stage II–IV; (4) Karnofsky Performance Status (KPS) score>=60; (5) Able to eat normally orally, with good adherence to nutritional therapy concepts and medical care; (6) Regularly receiving non-surgical treatments (e.g., chemotherapy, radiotherapy, immunotherapy) with an expected survival period of more than 6 months; (7) Presence of malnutrition or risk of malnutrition, with a PG-SGA score >=4; (8) Both patients and their families fully understand the potential benefits and risks of the study and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Combined severe cardiac, hepatic, or renal dysfunction; severe gastrointestinal diseases; uncontrolled chronic systemic diseases (e.g., diabetes, hypertension)?; (2) Concurrent use of other nutritional preparations that may interfere with trial outcomes?; (3) Contraindications to enteral or parenteral nutritional support?; (4) Pregnancy, lactation, or female patients of childbearing potential with positive baseline pregnancy tests?; (5) Allergy to soy products or severe allergic predisposition?; (6) Participation in other interventional clinical trials (including drugs, nutritional preparations, medical devices) within 4 weeks prior to screening?; (7) Investigator-determined unsuitability for study participation?.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Composition Analysis;Patient-Generated Subjective Global Assessment (PG-SGA) Score;Short Form Health Survey (SF-36) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Blood Count (CBC); | — |
Countries
China
Contacts
Public ContactWang Jinyun
Hefei Cancer Hospital,Chinese Academy of Sciences
Outcome results
None listed