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The Impact of Varying Replacement Fluid Temperature Settings on the Prevention of Early Hypotension in CRRT Patients

The Impact of Varying Replacement Fluid Temperature Settings on the Prevention of Early Hypotension in CRRT Patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102039
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

Intervention Group:For patients in this group, the replacement fluid and dialysate will be heated to 35.5°C during the first hour of treatment. From the second hour onward, the temperature will be ind
Control group:For patients in this group, the replacement fluid and dialysate will be heated to 37.5°C during the first hour of treatment. From the second hour onward, the temperature will be individu

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years and <= 80 years, regardless of gender; 2.Hospitalization in the intensive care unit of our hospital with a plan to undergo CRRT; 3.Use of vasoactive drugs at the initiation of CRRT treatment; 4.Ability to understand the study, provide consent, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with a systolic blood pressure < 90 mmHg or a mean arterial pressure < 65 mmHg prior to randomization; 2.Patients with an ear thermometer reading < 35°C or with thermoregulatory dysfunction; 3.Patients undergoing long-term hemodialysis.

Design outcomes

Primary

MeasureTime frame
Hypotensive Events;Hypothermic Events;

Secondary

MeasureTime frame
Number of Hypotensive Episodes;

Countries

China

Contacts

Public ContactYu Zhenyuan

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China

yuzhenyuan10@gmail.com+86 159 0068 4805

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026