Need to undergo painless gastroscopy
Conditions
Interventions
Experimental group (O1 group):Administer 1mg of oxaliplatin, followed by a single intravenous injection of 1-1.5mg/kg of propofol 1 minute later
Experimental group (O2 group):Administer 1.5 mg of oxaliplatin, followed by a single intravenous injection of 1-1.5 mg/kg of propofol 1 minute later
Control group (S group):Administer sufentanil at a dose of 0.1 µ g/kg, followed by a single intravenous injection of propofol at a dose of 1-1.5mg/kg 1 minute later
Sponsors
Xianyang Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age range: 18 to 65 years old; (2) ASA Level I-II; (3) BMI 18~30 kg/m^2; (4) Patients undergoing gastroscopy under elective sedation anesthesia
Exclusion criteria
Exclusion criteria: (1) Refusing to sign the informed consent form; (2) Expected difficult airway; (3) Known to be allergic to the drugs and ingredients used in this study; (4) Known or suspected gastrointestinal obstruction; (5) Acute or severe bronchial asthma; (6) Severe liver and kidney dysfunction; (7) Long term use of opioid drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Record the number of auxiliary airway operations to be performed during the examination (such as jaw lifting, patient posture adjustment, mask ventilation), minimum SpO2, and the number of times the endoscope is removed due to persistent hypoxemia; | — |
Countries
China
Contacts
Public ContactZhaiMiaomiao
Xianyang Central Hospital
Outcome results
None listed