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Factors associated with Discontinuation of Biologics and JAK inhibitors in Patients with Rheumatoid Arthritis

Factors associated with Discontinuation of Biologics and JAK inhibitors in Patients with Rheumatoid Arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500102023
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-05-09
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Interventions

tocilizumab (Tocilizumab 8mg/kg intravenous drip once a month):None
Etanercept (Etanercept 50mg by subcutaneous injection (qw)):None
Tofacitinib (Tofacitinib 5mg orally twice a day):None
Adalimumab (Adalimumab 40mg was subcutaneously injected every two weeks):None
Baritinib (Baritinib is taken orally at 2mg or 4mg per day):None
Upatinib (Upatinib is taken orally at 15mg per day):None

Sponsors

Taizhou Hospital of Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: All patients with rheumatoid arthritis who used biological agents and jak inhibitors in the Rheumatology and Immunology Department of Taizhou Hospital from 2021.1 to 2024.3 were included. The included drugs are adalimumab, etanercept, tocilizumab, tofacitinib, baritinib and upatinib.

Exclusion criteria

Exclusion criteria: Patients who received biological agents in clinical trials were excluded. The exclusion criteria are as follows: 1.Patients with ankylosing spondylitis and other connective tissue diseases except Sjogren's syndrome 2. Patients with clear mental disorders. 3. Patients without blood tests or with severe lack of data during treatment. 4 The use of biological agents or JAK inhibitors for purposes other than rheumatoid arthritis 5. Cancer patients

Design outcomes

Primary

MeasureTime frame
The patient stopped taking the medicine;

Secondary

MeasureTime frame
General information;

Countries

China

Contacts

Public ContactJing Pan

Taizhou Hospital of Zhejiang Province

panj4154@enzemed.com+86 139 6841 8055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026