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Probiotic therapy improves the prognosis of patients with atrial fibrillation: a controlled trial

Study the effect of probiotic intervention on prognosis of patients with atrial fibrillation: a controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500102017
Enrollment
Unknown
Registered
2025-05-07
Start date
2025-06-15
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation

Interventions

Probiotic intervention group:3g/d of Tongrentang probiotic powder (4.0×1010CFU containing L. hamnosus, L. Ruteri and other probiotics) was taken in the first two months after operation.
Control group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with atrial fibrillation scheduled for pulmonary vein isolation. (2) The age is greater than or equal to 18 years old and less than or equal to 80 years old. (3) Informed consent was signed voluntarily.

Exclusion criteria

Exclusion criteria: (1) Patients with severe structural heart disease (including valvular heart disease, myocardial infarction, hypertrophic obstructive cardiomyopathy, congenital heart disease, etc.). (2) Advanced heart failure patients with left ventricular ejection fraction 3.0mg/dL). (5) Patients with advanced malignant tumors. (6) Patients with severe complications such as pulmonary fibrosis, liver fibrosis and connective tissue diseases. (7) Patients with hyperthyroidism. (8) Patients older than 80 years old. (9) Taking other probiotic products within the past 15 days

Design outcomes

Primary

MeasureTime frame
Recurrent rate;Gut microbiota;Serum metabolomic;

Countries

China

Contacts

Public ContactKaijun Cui

West China Hospital, Sichuan University

cuikaijunscu@163.com+86 180 8060 2036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026