hepatocellular carcinoma
Conditions
Interventions
Conventional Laparoscopy Group:Hemihepatectomy performed using a conventional laparoscopic system
Multimodal Laparoscopy Group:Hemihepatectomy performed using a domestically developed multimodal laparoscopic system.
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Histologically confirmed or radiologically diagnosed primary hepatocellular carcinoma (HCC); 2.Age between 18 and 75 years; 3.ECOG performance status of 0–1; 4.Tumor localized to either the left or right hemiliver, with anticipated feasibility of hemihepatectomy; 5.No evidence of vascular invasion or distant metastasis; 6.Child-Pugh classification A or B; 7.Normal liver, renal, and bone marrow function.
Exclusion criteria
Exclusion criteria: 1.History of prior treatment for hepatocellular carcinoma (e.g., radiotherapy, chemotherapy, targeted or immunotherapy); 2.History of malignancies outside the liver; 3.Non-hepatocellular carcinoma pathology; 4.Clinical evidence of significant portal hypertension, such as esophageal varices, splenomegaly (>12 cm), or platelet count <10×10?/mL; 5.Presence of severe comorbidities involving other systems or organs that constitute contraindications to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of complications within 30 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| R0 resection rate;Intraoperative blood loss;Postoperative hospital stay;Overall surviva;Disease-free survival;Incidence of severe postoperative complications; | — |
Countries
China
Contacts
Public ContactShunli Shen
The First Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed