Diabetic Peripheral Neuropathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patients with Type 1 or Type 2 diabetes mellitus with a disease duration of more than 5 years; 2) Individuals aged 18 years or older.
Exclusion criteria
Exclusion criteria: 1) Presence of severe mental illness or language barriers; 2) Patients with malignant tumors; 3) Pregnant or lactating women; 4) Suspected active infections (such as active tuberculosis, pneumonia, etc.); 5) Severe liver and kidney dysfunction (alanine aminotransferase and/or aspartate aminotransferase > three times the upper limit of normal; estimated glomerular filtration rate <15 mL/min/1.73 m^2); 6) History of definite major adverse cardiovascular events; 7) Uncontrolled hyperthyroidism or hypothyroidism, pituitary-adrenal dysfunction, or other endocrine disorders; 8) Alcohol abuse or drug addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Olfactory Score;Sensory Thresholds;Glycosylated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical series;Diabetes Panel; | — |
Countries
China
Contacts
The First Affiliated Hospital of Harbin Medical University