Sick sinus syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A retrospective analysis was performed for patients with cardiac dual-chamber pacemakers, ICDs, and CRTs implanted in the First Hospital of Jiaxing City, the Affiliated Hospital of Jiaxing University from January 2019 to December 2025, with electrode leads implanted in the atria and ventricles, and good atrial sensing function. There were 1000 patients with AHRE events within 2 years of postoperative follow-up. The types of devices are ordinary dual-chamber pacemakers, and the brand of devices includes: Medtronic, Abbott, BIOTRONIK, Boston Scientific, and Creative Medical; Of these, 700 were used to build predictive models and 300 were used to validate predictive models.
Exclusion criteria
Exclusion criteria: Patients with severe hepatic insufficiency (aspartate aminotransferase/alanine aminotransferase levels >=3 times the upper limit of normal) or severe renal insufficiency (serum creatinine level >=3.5 mg/dL or creatinine clearance <=30 mL/min) were excluded, including those requiring dialysis; Pregnant or lactating patients; or those with malignancy, severe valvular heart disease, or a life expectancy of <=12 months since enrollment. Patients with high-frequency atrial events prior to device implantation, e.g., patients with brachy-slow syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atrial high-rate episodes; | — |
Countries
China
Contacts
The Affiliated Hospital of Jiaxing University and the First Hospital of Jiaxing City