Postoperative pain
Conditions
Interventions
Group A1:Ropivacaine 75mg+Dexamethasone 5mg+Epinephrine 50ug+NS to 50 for incision infiltration (30ml)
Group C:PCIA—Sufentanil 150ug+5-HT3 receptor antagonist 1 vial+0.9% NS 150ml.
Group A0:Ropivacaine 75mg+Epinephrine 50ug+NS to 50 for incision infiltration (30ml)
Group A2:Ropivacaine 75mg+Dexmedetomidine 50ug+Dexamethasone 5mg Epinerine 50ug+NS to 50ml for incision infiltration (30ml)
Group A3:Ropivacaine 75mg+Dexmedetomidine 50ug+Ketorolac 30mg+ Dethasone 5mg+Epinephrine 50ug+NS to 50ml for incision infiltration (30ml)
Sponsors
Guizhou Provincial People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Emergency or elective cesarean section surgery, patients aged 18-50 years old, and received neuraxial anesthesia
Exclusion criteria
Exclusion criteria: 1. Unable to provide informed consent; 2. Unable to understand written or spoken language; 3. Severe comorbidities (such as severemonary hypertension, heart failure, etc.) 4. Contraindications to neuraxial anesthesia: low coagulation function; platelet count <80×10^9/L; pregnant women who refuse or cannot cooperate with the procedure; pregnant women with shock, hypovolemia, or other hemodynamic instability; pregnant women with severe deformities, trauma, etc., which may affect puncture; pregnant women with infection at the puncture site or bacteremia that could lead to neuraxial; pregnant women with central nervous system diseases, especially spinal cord or spinal nerve root lesions; other conditions that may lead to neuraxial bleeding or infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical Rating scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative opioid use within 72 hours;Postoperative opioid use within 30d;Time to Bowel Movement;Time to oral intake;Time to Ambulation;Post-operative Nausea and Vomiting;Length of hospitalization;Number of Participants With Readmission to the Hospital;Patient reported quality of recovery and quality of life as determined by QoR-15 score;Occurrence of severe and minor complications within 30 days postoperatively;Cost per patient; | — |
Countries
China
Contacts
Public ContactKaiyun Fang
Guizhou Provincial People's Hospital
Outcome results
None listed