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Research on the regulatory mechanism of bone metabolism in the central nervous system

Research on the regulatory mechanism of bone metabolism in the central nervous system

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101946
Enrollment
Unknown
Registered
2025-05-06
Start date
2022-10-30
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postmenopausal osteoporosis

Interventions

Electroacupuncture group:Select acupoints for Shenshu (BL23). After acupuncture, connect the Shenshu point with electroacupuncture, continuous wave, frequency 2Hz, voltage 2V, and leave the needle for
Drug group :Alendronate Sodium Vitamin D3 Tablets (II)
Normal group:None

Sponsors

Shenzhen Bao'an Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Age 45-70 years old; 2.Bone density value is -2.5<T<-1.

Exclusion criteria

Exclusion criteria: 1. Secondary osteopenia; 2. Treated with anti-osteoporosis drugs; 3. Severe mental illness.

Design outcomes

Primary

MeasureTime frame
fMRI;Bone mineral density;Bone metabolism markers;Estrogen;Norepinephrine;

Secondary

MeasureTime frame
Clinical bone pain score (McGill Pain Questionnaire Short-Form);Osteoporosis symptom score;Hamilton Depression Scale;Hamilton Anxiety Scale;

Countries

People's Republic of China

Contacts

Public ContactJunquan Liang

Shenzhen Bao'an Chinese Medicine Hospital

gliangzixuan@163.com+86 130 4346 8227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026