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Application of binocular asynchronous visual stimulation technology for form deprivation amblyopia

Application of VR based binocular asynchronous visual stimulation technology for form deprivation amblyopia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101938
Enrollment
Unknown
Registered
2025-05-06
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

form deprivation amblyopia,Congenital cataract

Interventions

Asynchronous visual stimulation treatment group:none
control:none

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with amblyopia due to deprivation of visual input by clinical examination; 2. Bilateral cataracts, having undergone cataract extraction and intraocular lens implantation surgery for more than 3 months and wearing appropriate glasses for refractive correction; 3. The amblyopic eye is the dominant one for fixation; 4. No obvious strabismus or nystagmus; 5. Apart from refractive correction, no other amblyopia treatment has been received for the past 8 weeks; 6. The patient can fixate on the central target of the VR device presenting non-synchronous binocular visual stimuli; 7. The subject can accept viewing stereoscopic images; 8. The subject can complete the treatment and follow-up as required by the protocol during the experiment.

Exclusion criteria

Exclusion criteria: 1. history of previous ophthalmic surgeries other than simple cataract extraction, intraocular lens implantation and strabismus surgery. 2. history of skin allergy to eye patches or eye masks in the past. 3. Ophthalmic screening revealed other possible organic eye diseases that might affect vision besides cataract. 4. Premature infants, low birth weight infants, history of perinatal hypoxia, severe developmental delay, or other systemic diseases that might affect vision. 5. Unable to accept viewing stereoscopic vision images, such as those with vertigo, Meniere's syndrome, etc. 6. Unable to complete treatment or follow-up as per the protocol requirements during the experiment.

Design outcomes

Primary

MeasureTime frame
Best corrected visual acuity;Contrast sensitivity VEP Strabismus degree, refractive error, near stereo vision, far stereo vision, degree of monocular suppression;

Countries

China

Contacts

Public ContactLi Ruoshi

Peking University First Hospital

lirs1991@126.com+86 10 83572336

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026