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The Clinical Application of Ciprofol in General Anesthesia

The Clinical Application of Ciprofol in General Anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101918
Enrollment
Unknown
Registered
2025-05-06
Start date
2025-05-06
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recovery quality

Interventions

Group C:total intravenous anesthesia based on cipropol:Anesthesia was induced with cyclopropofol 0.4 mg/kg (with supplemental doses of 0.2 mg/kg as needed), sufentanil 0.4 ug/kg, and cisatracurium 0.2
Group P:total intravenous anesthesia based on propofol:For anesthesia induction, propofol 2mg/kg was administered (with an optional supplemental dose of 1mg/kg if needed), followed by sufentanil 0.4ug

Sponsors

Nanjing Stomatological hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing elective oral and maxillofacial surgery under general anesthesia with an expected surgery duration of <= 2 hours; (2) Patients willing to undergo total intravenous anesthesia; (3) Patients aged 18-65 years with a BMI of 18-30 kg/m^2 and classified as ASA I-III; (4) Patients with no surgical history in the past three months; (5) Patients and their family members agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with allergies to the anesthetic drugs or soybeans used in this study; (2) Patients with a history of alcohol, sedatives, analgesics, psychoactive drug abuse, or addiction; (3) Patients with organ dysfunction, arrhythmias, or congenital heart disease; (4) Patients with severe airway obstruction, such as sleep apnea syndrome or craniofacial syndromes; (5) Patients with severe visual or auditory impairments, or difficulties in communication; (6) Patients undergoing emergency surgery or surgery during pregnancy; (7) Patients who refuse to participate in the study.

Design outcomes

Primary

MeasureTime frame
QoR-15 score 24 hours post-surgery;Incidence of hypotension during induction and maintaince period;

Secondary

MeasureTime frame
QoR-15 score 48 hours post-surgery;The number of administrations and the total amount of vasoactive drugs;Time to lost of consciousness;Length of hospital sta;Recovery time and extubation time;Adverse events;The number of additional drug administrations;

Countries

China

Contacts

Public ContactBao-jian Zhao

Nanjing Stomatological hospital

mzkzbj@126.com+86 181 0518 0203

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026