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The impact of preemptive analgesia with hydromorphone on postpartum depression in women

The impact of preemptive analgesia with hydromorphone on postpartum depression in women

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101915
Enrollment
Unknown
Registered
2025-05-06
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy, childbirth, or the puerperium

Interventions

Intravertebral labor analgesia group:Intravertebral analgesia
Hydromorphone preemptive analgesia group:Preemptive analgesia
Natural labor group:No Relieve pain

Sponsors

Jiangxi Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1.Women who signed the informed consent and delivered vaginally-had normal reading comprehension and communication skills, and the standard score of ZUNG's Self-Rating Depression Scale (SDS) was less than 50 points. 2.Parturients are graded according to ASA: I-II 3.Vaginal natural delivery is suitable for prenatal examination by obstetricians 4. Meet the following conditions: first birth, single birth, Full term, head pregnancy.

Exclusion criteria

Exclusion criteria: 1.Contraindications of epidural puncture 2.Basal body temperature >= 37.5 ? 3. Age 40 years 4.A history of drug abuse 5.There are indications of cesarean section 6.Pregnant women belong to the following high-risk pregnancy range: pre-eclampsia, placenta previa, placental abruption, gestational diabetes, hypertension syndrome, heart function >= II, hyperthyroidism and other diseases, abnormal heart, liver, pancreas and kidney function . 7. Pre-operative examination of premature rupture of membranes,labor 8 h or midcourse to section.

Design outcomes

Primary

MeasureTime frame
Postpartum depression;

Secondary

MeasureTime frame
Serum IL-6 and 5-HT concentrations;

Countries

China

Contacts

Public ContactLiu Yanlong

Jiangxi Provincial People's Hospital

280169526@qq.com+86 159 7913 6043

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026