Gastric cancer
Conditions
Interventions
Control group:The same dose of normal saline is given after endotracheal intubation and intraoperatively. Postoperative analgesic pump sufentanil 4ug/kg (up to 250 ug) diluted to 200ml with normal sal
Experimental group:Endotracheal intubation was followed by esketamine 0.2 mg/kg for 10 minutes, followed by 0.1 mg/kg/hour until the end of surgery. Postoperative analgesic pump sufentanil 4 ug/kg (up
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Expected to undergo laparoscopic radical gastrectomy; 2. Age 18-80 years old; 3. Patients with ASA grade I.-III; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Difficulty communicating or understanding; 2. There are contraindications to esketamine; 3. Long-term use of opioids or non-steroidal drugs; 4. Refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of moderate to severe pain within 48 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions;Sleep quality;Quality of postoperative recovery;Postoperative delirium; | — |
Countries
China
Contacts
Public ContactXu Pingbo
Zhejiang Cancer Hospital
Outcome results
None listed