Alveolar ridge is deprived of functional stimulation after tooth loss, which, if not promptly addressed, can lead to significant alveolar bone atrophy. Additionally, alveolar bone defects may arise due to inflammation, tumors, trauma, or developmental disorders affecting the dentition. These conditions can impede the clinician's ability to restore dental function during implant therapy, often nece
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient with 20-40 year old; 2.Patient need tooth implantation; 3.Complete blood count and coagulation profile are within normal limits, and the patient has not taken any medications known to affect leukocyte or platelet function within the preceding three months; 4.The patient is in good general health, free from systemic conditions such as diabetes mellitus, hypertension, and cardiovascular diseases, and presents no contraindications for surgical procedures, thereby meeting the inclusion criteria for clinical research participation.
Exclusion criteria
Exclusion criteria: 1.Patients with infectious diseases; 2.Smokers; 3.Women during menstruation or lactation; 4.Failure to obtain liquid plasma matrix after centrifugation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The microstructural morphology of sticky bone and the in vitro release kinetics of growth factors.; | — |
Countries
China
Contacts
Peking University Hospital of Stomatology