GBP4 as a potential biomarker for the diagnosis of Crohn's disease and its relationship to M1 macrophage infiltration

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500101875

Enrollment

Unknown

Registered

2025-04-30

Start date

2023-01-01

Completion date

Unknown

Last updated

2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn disease

Interventions

Active inflammation group:None

Normal intestinal tissue group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Intestinal samples were collected from patients diagnosed with Crohn's disease (older than 18 years old, younger than 80 years old) and undergoing surgery in our hospital from 2023 to 2024, and their normal intestinal tissues were used as the control group.

Exclusion criteria

Exclusion criteria: Patients with Crohn's disease have intestinal malignancies, or giant cell infection, or intestinal tuberculosis, or intestinal fistulas, or other malignancies.

Design outcomes

Primary

Measure	Time frame
GBP4 protein expression and macrophage immune infiltration;	—

Countries

China

Contacts

Public ContactHeng Shi

The Central Hospital of Shaoyang

pq1232020@163.com+86 177 5266 6290

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026