Gastric cancer/astroesophageal junction adenocarcinoma
Conditions
Interventions
Manual Anastomosis Group:Folded-layered manual esophagojejunal anastomosis
Stapled Anastomosis Group:Stapled esophagojejunal anastomosis
Sponsors
Gansu Wuwei Tumor Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?1.Preoperative diagnosis? confirmed by gastroscopy and pathological examination as ?gastric cancer? or ?adenocarcinoma of the esophagogastric junction (Siewert type II/III)?. ?2.Clinical stage? classified as ?cT2-4aN+M0? and planned for ?totally laparoscopic total gastrectomy?. 3.Patients who demonstrated ?significant clinical response? after ?neoadjuvant chemotherapy? or ?immunotherapy?. ?4.Complete and available clinicopathological data?. ?5.Written informed consent? was obtained from all patients prior to surgery.
Exclusion criteria
Exclusion criteria: ?1.Age 75 years? 2?.Emergency surgery? for complications (e.g., hemorrhage, perforation, obstruction) ?3.Pathologically confirmed T4b (invading adjacent organs)? or ?M1 (distant metastasis)? intraoperatively/postoperatively ?4.Combined organ resection? or ?palliative resection? during surgery 5.History of ?preoperative radiotherapy? ?5.ASA physical status classification > Class III
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of anastomotic leakage;Cost of intraoperative consumables; | — |
Secondary
| Measure | Time frame |
|---|---|
| Digestive tract reconstruction time;Total operating time;Intraoperative blood loss;Time of first postoperative expiration;Time of first fluid intake;Post-operative hospitalization;Overall complication rate;Overall cost of hospitalization;Incidence of anastomosis-related complications;Unplanned 30-day postoperative rehospitalization rate; | — |
Countries
China
Contacts
Public ContactNie Peng
Gansu Wuwei Tumor Hospital
Outcome results
None listed