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Real-world study on the safety and efficacy of Linaclotide combined with Ultra-low-volume Polyethylene Glycol for bowel preparation in Low-Risk Patients

Real-world study on the safety and efficacy of Linaclotide combined with Ultra-low-volume Polyethylene Glycol for bowel preparation in Low-Risk Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101833
Enrollment
Unknown
Registered
2025-04-30
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bowel preparation

Interventions

Sponsors

The Third People's Hospital of Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1)Outpatients or individuals undergoing physical examination in the Department of Gastroenterology who are scheduled to undergo colonoscopy and are >18 years old; 2)Patients at low risk of inadequate bowel preparation (excluding any of the following risk factors for inadequate bowel preparation: age >70 years, chronic constipation, diabetes, Parkinson’s disease, stroke, history of spinal disease or spinal cord injury, history of gastrointestinal surgery, BMI >25 kg/m^2, use of tricyclic antidepressants or narcotics); 3)Those who opt for the PEG regimen for bowel preparation are included.

Exclusion criteria

Exclusion criteria: 1)Individuals with mental illness or those unable to cooperate with the study; 2)Pregnant or lactating women; 3)Patients with known allergies to the trial medication; 4)Those who refuse to participate in this study or undergo related medical observation and data collection.

Design outcomes

Primary

MeasureTime frame
The rate of adequate bowel preparation ;

Secondary

MeasureTime frame
Total BBPS;Sections BBPS;Polyp detection rate;Adenoma detection rate;Cecal Intubation Rate;Cecal Intubation Time;Withdrawal Time;Feeling score of patients during colonoscopy;adverse reaction;Quality of sleep;Willingness to repeat the same bowel preparation;Compliance;Bubble Score;Physician Satisfaction;Changes of Electrolyte Levels Before and After Bowel Preparation;Comparison with Previous Bowel Preparation;

Countries

China

Contacts

Public ContactZhang Chen; Sun Xiaobin

The Third People's Hospital of Chengdu

xbsun1197@163.com+86 189 8077 7209

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026