common wart and plantar wart
Conditions
Interventions
Superpulsed CO2 laser combined with ALA-PDT group:Superpulsed CO2 laser combined with ALA-PDT
Novel Drug-Delivery Photodynamic Therapy group(Intralesional injection photodynamic therapy group):Novel Drug-Delivery Photodynamic Therapy (Intralesional injection photodynamic therapy)
Sponsors
Huadong Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
10 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 10 and 80 years old, regardless of gender. 2. Clinical diagnosis of common warts or plantar warts. 3. Duration of the disease >=2 years or previous treatment with multiple therapeutic methods with unsatisfactory results. 4. Have not received systemic or topical antiviral and immunotherapy within 2 months prior to enrollment. 5. The patient has signed an informed consent form and agreed to be followed up regularly.
Exclusion criteria
Exclusion criteria: 1. Known history of allergy to red-light or ALA. 2. History of severe hypertrophic scar or keloids. 3. Those with significant bleeding tendency. 4. Patients with psychological disorders such as blood or trauma phobia. 5. Patients with other diseases that may affect the evaluation of the efficacy of the treatment. 6. Those with severe immunocompromise; 7. Those suffering from serious internal diseases. 8. Pregnant or lactating women; 9. Other patients who, in the opinion of the investigator, are not suitable to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage of viral wart volume reduction; | — |
Secondary
| Measure | Time frame |
|---|---|
| safety;Relapsing rate;Mechanism exploration;effective rate;cure rate; | — |
Countries
China
Contacts
Public ContactLei Shi
Huadong Hospital, Fudan University
Outcome results
None listed