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Dose effect relationship of bupivacaine liposome erector spinae muscle plane block under ultrasound guidance for the treatment of postherpetic neuralgia

Dose effect relationship of bupivacaine liposome erector spinae muscle plane block under ultrasound guidance for the treatment of postherpetic neuralgia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101787
Enrollment
Unknown
Registered
2025-04-29
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes zoster

Interventions

Bupivacaine liposomes 0.887% (L1 group):Ultrasound guided erector spinae plane block with bupivacaine liposome concentration of 0.887%
Bupivacaine liposomes0.76% (L2 group):Ultrasound guided erector spinae plane block with bupivacaine liposome concentration of 0.76%
Bupivacaine liposomes0.665% (L3 group):Ultrasound guided erector spinae plane block with bupivacaine liposome concentration of 0.665%
Bupivacaine liposomes0.59%(L4 group):Ultrasound guided erector spinae plane block with bupivacaine liposome concentration of 0.59%
Bupivacaine liposomes0.532%(L5 group):Ultrasound guided erector spinae plane block with bupivacaine liposome concentration of 0.532%

Sponsors

Shaoxing Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients diagnosed with postherpetic neuralgia who came to Shaoxing Second Hospital and Zhuji Second People's Hospital for treatment. 1.Age >=18 years old; 2. Patients with confirmed diagnosis of herpes zoster in the chest, back or abdomen, and persistent pain for more than one month after skin damage has healed; 3.Visual Analog Scale (VAS) score >= 4 points.

Exclusion criteria

Exclusion criteria: 1. Patients with combined blood system, severe heart and lung dysfunction, and severe liver and kidney dysfunction; 2. Individuals with abnormal coagulation function; 3. Individuals with skin damage or local infection at the puncture site; 4. VAS score <=3 points, local rash at the treatment site has not healed; 5.Those who cannot tolerate the use of drugs in this experiment or do not agree to participate in the modified project.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale,VAS;

Secondary

MeasureTime frame
Quality of sleep,QS;

Countries

China

Contacts

Public ContactLu Cai

Shaoxing Second Hospital

cailu345@163.com+86 159 6758 8551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026