Child myopia
Conditions
Interventions
Group 1: 0.01% atropine sulfate eye drops, once daily.
Group 2:0.004% atropine sulfate eye drops, once daily.
Sponsors
Hebei Eye Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Written informed consent signed by the child and legal guardian has been obtained. 2. Children aged 6 to 12 years (including the cut-off value). 3. After cycloplegia, the binocular spherical power measured by computer optometry: myopia diopter is greater than or equal to 50 degrees and less than or equal to 400 degrees. 4. Binocular astigmatism detected by computer optometry after cycloplegia = 15-0.25* age.
Exclusion criteria
Exclusion criteria: 1. Subjects who may suffer from eye diseases that affect vision or refractive error (such as cataract and other lens damage diseases, glaucoma, maculopathy, keratopathy, retinitis pigmentosa, retinal detachment, severe vitreous opacity, etc.). 2. Systemic diseases: immune system diseases, central nervous system diseases, Down syndrome, asthma, severe cardiopulmonary function, severe liver and kidney dysfunction. 3. Both eyes or one eye have dominant strabismus or any other pathological changes of the eye or acute inflammatory diseases of the eye. 4. Have used myopia control treatment methods and drugs in recent half a year or three months: such as atropine or pirenzepine; Instrument treatment: orthokeratology lens, multifocal soft lens, multifocal hard lens, functional frame glasses, etc. 5. Drugs that have been used systemically or locally within 3 months before screening to affect the efficacy evaluation, such as anticholinergic drugs: atropine, pirenzepine;Choline mimetics: pilocarpine, etc. 6. Those who are allergic to atropine, tropicamide and other drugs used in this study. 7. Those who have participated in clinical trials of other drugs within 3 months before screening. 8. Other circumstances that the researcher deems inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 48/2000 Correlation between the variation of system parameters and equivalent sphere, AL change in December; | — |
Secondary
| Measure | Time frame |
|---|---|
| Trends in changes in regulatory system parameters (adjustment range, adjustment sensitivity, etc.) at different follow-up nodes compared to the baseline; | — |
Countries
China
Contacts
Public ContactLi Shanxue
Hebei Eye Hospital
Outcome results
None listed