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The effect of gut microbiota on anxiety-like and depression-like behaviors in the elderly

The effect of gut microbiota on anxiety-like and depression-like behaviors in the elderly

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101770
Enrollment
Unknown
Registered
2025-04-29
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The elderly of anxiety-like and depression-like behaviors

Interventions

The normal elderly people:None
Elderly people with anxiety-like and depression-like behaviors:None

Sponsors

Rugao People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 110 Years

Inclusion criteria

Inclusion criteria: (1) Age >= 60 years.healthy adult volunteers in China;(2) Possess the ability to read, understand spoken language and copperate with completing the Patient Health Questionnaire-9 and the Hamilton Scale;(3) Voluntarily participate in this study and sign the sign the informed consent form;.

Exclusion criteria

Exclusion criteria: (1) Refused to participate in the research;(2) Unable to communicate due to coma, dementia or language disorders; (3) Had a history of mental illness such as bipolar disorder and schizophrenia; (4) Had experienced serious heart, kidney, liver, gastrointestinal tract, infectiois diseases or cancer; (5) Had a history of neurological diseases (traumatic brain injury, stroke, and Parkinson's disease);(6) Refused to communicate or had been identified anxiety or depression diseases.

Design outcomes

Primary

MeasureTime frame
Sequencing of gut microbiota;Patient Health Questionnaire-9;Hamilton Scale;

Secondary

MeasureTime frame
Inflammatory factor;Oxytocin level;

Countries

China

Contacts

Public ContactXinying Zhang

Rugao People's Hospital

xinying20180205@163.com+86 153 6515 0033

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026