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Correlation analysis of vascular spasm with local brain tissue oxygen saturation and plasma endothelin-1 in patients with aneurysmal subarachnoid hemorrhage

Correlation analysis of vascular spasm with local brain tissue oxygen saturation and plasma endothelin-1 in patients with aneurysmal subarachnoid hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101757
Enrollment
Unknown
Registered
2025-04-29
Start date
2021-01-02
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aneurysmal subarachnoid hemorrhage

Interventions

rScO2 normal group:None
rScO2 abnormal group:None

Sponsors

Zigong Fourth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. confirmed as aSAH by computed tomography (CT) upon admission; 2. confirmed aneurysm rupture by digital subtraction angiography (DSA); 3. age greater than or equal to 18 years old; 4. patient was first diagnosed and admitted to the hospital within 24 hours of onset; 5. complete clinical and laboratory data.

Exclusion criteria

Exclusion criteria: 1. history of cerebrovascular disease or neurological disorders in the past; 2. serious complications occurred during hospitalization, such as sepsis, liver and kidney dysfunction, etc; 3. merge autoimmune or blood related diseases; 4. pregnant or breastfeeding women; 5. incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Plasma endothelin-1;Local brain tissue oxygen saturation;—

Secondary

MeasureTime frame
Degree of vasospasm;Coma time;mortality;Neurological deficits occur;—

Countries

China

Contacts

Public ContactChenghao Yang

Zigong Fourth People's Hospital

chaoyangzigong4@163.com+86 186 8131 0624

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026