Breast Cancer
Conditions
Interventions
Control group (Group OA):Inject physiological saline intravenously 10 minutes before anesthesia induction.
Control group (Group OFA):Inject dexmedetomidine 0.6 µ g/kg (prepared with physiological saline) intravenously 10 minutes before anesthesia induction.
Sponsors
First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Elective modified radical mastectomy for breast cancer in our hospital; 2. Age 18-65 years; 3. ASA classification II or III; 4. Body mass index (BMI) 18.5 - 24.9 kg/m²; 5. Patients who agree to participate in this study and sign the informed consent form; 6. Preoperative Trait Anxiety Inventory (STAI) score of 20-44;
Exclusion criteria
Exclusion criteria: 1. Chronic pain with long-term use of opioids or nonsteroidal anti-inflammatory drugs (NSAIDs); 2. Infection, ulceration, peripheral neuropathy, or coagulation dysfunction at the puncture site; 3. Cerebrovascular disease or psychiatric disorders that may affect nerve block and postoperative assessment; 4. Presence of severe dysfunction in major organs such as the heart, liver, kidneys, or lungs; 5. Patients with contraindications to atropine;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative State-Trait Anxiety Inventory Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic monitoring indicators;The incidence of postoperative adverse reactions;Quality of Recovery-15 (QoR-15) score;Numerical Rating Scale (NRS) score;Time of tracheal extubation;The number of postoperative analgesic pump compressions;Length of stay in the recovery room.;Preoperative Trait Anxiety Inventory Score; | — |
Countries
China
Contacts
Public ContactShihong Li
First Affiliated Hospital of Gannan Medical University
Outcome results
None listed