None
Conditions
Interventions
Control group:None
Experimental group:None
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Pregnant women aged 18 years or older, classified as American Society of Anesthesiologists (ASA) grade II-III. 2.Undergoing planned cesarean section with an expected high risk of hemorrhage and vaginal blood loss >100 mL (meeting at least one of the following criteria: complete placenta previa, placenta accreta, history of postpartum hemorrhage, twin pregnancy). 3.Willing to participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients or their families refuse to participate in the study. 2.Technical contraindications (e.g., severe hemolysis). 3.Rh-negative patients or those with blood disorders, autoimmune diseases, acute fatty liver of pregnancy (AFLP), or HELLP syndrome. 4.Patients who received anticoagulation therapy preoperatively, underwent allogeneic blood transfusion within the past three months, participated in other clinical studies during pregnancy, or are unable to undergo vaginal blood salvage. 5.Presence of conditions that may hinder study participation, such as psychiatric disorders or language comprehension difficulties. 6.Patients with sickle cell anemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The positive rate of microbial culture of vaginal blood and peritoneal blood after washing and filtration; | — |
Secondary
| Measure | Time frame |
|---|---|
| The distribution of microbial species in the filtered vaginal blood after recycling;The distribution of microbial species in the filtered peritoneal blood after recycling;The positive rate of microbial culture of vaginal secretions after disinfection;The distribution of microbial species in peripheral blood;Amount of vaginal bleeding;Changes in white blood cell count and neutrophil count before and after the operation;Antibiotics used: The duration, types and concentrations of antibiotics used before and after the operation.;The distribution of microbial species in peripheral blood; | — |
Countries
China
Contacts
Public ContactTian Hang
The Affiliated Women and Children’s Hospital of Guangzhou Medical University
Outcome results
None listed