Liver injury after laparoscopic hepatectomy
Conditions
Interventions
experimental group:Paravertebral nerve block (T7, T9 two segments, bilateral, ropivacaine dose of 0.5%, 10ml per site)
Sponsors
Department of Anesthesiology, First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients undergoing laparoscopic partial hepatic resection
Exclusion criteria
Exclusion criteria: 1. Severe decompensation of liver and kidney function before surgery; 2. Age 80 years old; 3. Patients with infectious diseases in the skin and soft tissues at the injection site; 4. Those with severe bleeding tendency; History of cerebral infarction or cerebral hemorrhage within 5 or 6 months; History of unstable angina pectoris or myocardial infarction within 6 or 6 months; 7. ASA > Level III; 8. Predicted FEV1<50% for severe lung disease; 9. The patient has a history of malignant tumors, or other malignant tumors found in preoperative examination; 10. Severe mental illness; 11. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase on the first postoperative day; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of first feeding;time for drain removal;duration of hospitalization;preoperative and postoperative day 1 IL-6;preoperative and postoperative day 1 IL-1;preoperative and postoperative day 1 IL-10;preoperative and postoperative day 1 TNF-a;preoperative and postoperative day 1 SOD;preoperative and postoperative day 1Cor;preoperative and postoperative day 1NE;preoperative postoperative day 1 and postoperative day 5 AST;preoperative postoperative day 1 and postoperative day 5 TBIL; | — |
Countries
China
Contacts
Public ContactNing Jiaolin
Department of Anesthesiology, The First Affiliated Hospital of the Army Medical University
Outcome results
None listed