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Effect of metabolic syndrome and central sensitization on pain and function following total knee arthroplasty

Effect of metabolic syndrome and central sensitization on pain and function following total knee arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101745
Enrollment
Unknown
Registered
2025-04-29
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Neither metabolic syndrome nor central sensitization group:None
Metabolic syndrome group:None
Central sensitization group:None
Both metabolic syndrome and central sensitization group:None

Sponsors

The first hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Primary osteoarthritis 2. Adult patients (age 18-80 years) undergoing unilateral primary total knee arthroplasty 3. American Society of Anesthesiologists score (ASA) of 1-3.

Exclusion criteria

Exclusion criteria: 1. Rheumatoid arthritis 2. Suspected infection 3. Analgesic use within one month prior to surgery 4. Mental disease 5. Incomplete preoperative data 6. Incomplete follow-up data at 1 year postoperatively

Design outcomes

Primary

MeasureTime frame
Achievement rates of the minimal clinically important difference;—

Secondary

MeasureTime frame
Preoperative Western Ontario McMaster University Osteoarthritis Index (WOMAC) score;Western Ontario McMaster University Osteoarthritis Index (WOMAC) score at 3 months postoperatively;Western Ontario McMaster University Osteoarthritis Index (WOMAC) score at 12 months postoperatively;—

Countries

China

Contacts

Public ContactQi Xin

The first hospital of Jilin University

dr.qixin@jlu.edu.cn+86 158 4307 3202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026