Breast cancer
Conditions
Interventions
Gold Standard Group:Paraffin pathology interpretation
ES assisted preservation of nipple areola complex (NAC) in mastectomy (NSM):ES interpretation: performed by a breast surgeon and pathologist after at least one hour of ES training
Frozen pathological interpretation group for routine assisted preservation of nipple areola complex (NAC) in mastectomy:Conventional frozen pathological interpretation
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age over 18 years old; 2.Patients diagnosed with breast cancer who meet the criteria of nipple areola complex (NAC) preserving mastectomy evaluated by doctors; 3.Not receiving radiation therapy before surgery; 4.The subjects voluntarily sign the informed consent form or are exempted from signing after review and approval by the ethics committee;
Exclusion criteria
Exclusion criteria: 1.Intraoperative evaluation of patients who changed to other breast cancer operations; 2.Unable to obtain paraffin pathology report; 3.Intraoperative dye allergy; 4.Patients with clinical or imaging evidence of nipple/areola involvement before surgery, including Paget's disease, nipple haemorrhage, inflammatory breast cancer, and/or imaging results suggest that the nipple or tissues under the areola are involved in malignant lesions, and retaining NAC cannot obtain a negative margin; 5.Accompanied with hypertension, diabetes and other basic diseases, smoking, and surgery under areola; 6.The anatomical characteristics of the breast itself, such as large and sagging breasts (NAC distance from the folds below the breast>8 cm, distance from the sternotomy to the nipple>27 cm);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complications;Operational efficiency; | — |
Countries
China
Contacts
Public ContactYu Yang
Zhejiang Cancer Hospital
Outcome results
None listed