Colorectal tumor
Conditions
Interventions
The group with an inhalation oxygen concentration of 40% (Group T1):After rapid sequence induction and fixation of the tracheal tube, the ventilator parameters were adjusted with an oxygen-to-air rati
The group with an inhalation oxygen concentration of 50% (Group T2):After rapid sequence induction and fixation of the tracheal tube, the ventilator parameters were adjusted, with the ratio of oxygen
The group with an inhalation oxygen concentration of 60% (Group T3):After rapid sequence induction and fixation of the tracheal tube, the ventilator parameters were adjusted with the ratio of oxygen t
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with laparoscopic colorectal tumor resection under general anesthesia in the First Affiliated Hospital of Guangxi Medical University, ASA grade II-III, cardiac function grade I-II, mechanical ventilation time >= 2 hours, age >= 18 years, and signed informed consent.
Exclusion criteria
Exclusion criteria: Known allergy to oxygen or other inhaled narcotic drugs;Machine ventilation <2 hours; Patients participating in other clinical trials; A family history of malignant hyperthermia, pseudocholinesterase deficiency, and family genetic disorders; Have severe arrhythmia,or have heart valve disease requiring surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DO2;VO2;O2ER;Lac;Venous oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Absolute neutrophils/absolute lymphocytes;Platelet/lymphocyte absolute;Platelet count× neutrophil count/lymphocyte count; | — |
Countries
China
Contacts
Public ContactZhang Guangying
The Fist Affiliated Hospital of Guangxi Medical University
Outcome results
None listed