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Comparison of Corneal Epithelial Remodeling and Analysis of Related Factors After FS-LASIK and SMILE

Comparison of Corneal Epithelial Remodeling and Analysis of Related Factors After FS-LASIK and SMILE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101708
Enrollment
Unknown
Registered
2025-04-28
Start date
2022-12-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

Sponsors

Urumqi Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patient has a personal desire for vision correction surgery with reasonable expectations, age between 18 and 45 years old, and has maintained relatively stable refractive status (with annual refractive changes =480 µm, predicted postoperative residual corneal stromal thickness >=280 µm, spherical power between -1.00 D and -9.00 D, and cylindrical power <= -3.00 D.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: Exclude hyperopia and mixed astigmatism, as well as corneal ectatic disorders , moderate-to-severe dry eye syndrome, and other ocular pathologies. Patients must have no history of prior ocular surgery or trauma, psychiatric conditions or autoimmune diseases. Preoperative preparation requires: discontinuation of soft contact lenses for 1-2 weeks, rigid gas-permeable (RGP) lenses for >=1 month, and orthokeratology lenses for >=3 months. Intraoperative considerations include: significant dark spots or opaque bubble layer (OBL) affecting laser scanning quality, loss of suction during the procedure. Postoperative precautions involve: nonstandard medication use, complications such as elevated intraocular pressure, delayed visual recovery, corneal flap striae, or other surgical complications, noncompliance with prescribed eye drops, failure to attend scheduled follow-ups, or loss of follow-up data.

Design outcomes

Primary

MeasureTime frame
corneal epithelial thickness;corneal thickness;

Secondary

MeasureTime frame
Visual acuity;Refractive power;Corneal aberration;

Countries

China

Contacts

Public Contactzhangyangjing

Urumqi Aier Eye Hospital

m17609004690@163.com+86 176 0900 4690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026