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Analysis of the Analgesic Effect of Liposomal Bupivacaine Transversus Abdominis Plane Block on Postoperative Pain Management in Laparoscopic Colorectal Cancer Resection

Analysis of the Analgesic Effect of Liposomal Bupivacaine Transversus Abdominis Plane Block on Postoperative Pain Management in Laparoscopic Colorectal Cancer Resection

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101706
Enrollment
Unknown
Registered
2025-04-28
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Ropivacaine transversus abdominis plane block group (control group R):Ropivacaine transversus abdominis plane block
Bupivacaine liposomal transversus abdominis plane block group (experimental group LB):Bupivacaine liposomal transversus abdominis plane block

Sponsors

Second Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Laparoscopic colorectal surgery under general anesthesia was performed; 2. Age: 18-75 years old; 3. BMI 18~28 kg/m^2; 4. No gender limitation; 5. Clear language and consciousness, able to cooperate with research; 6. Be aware of this study and sign informed consent;

Exclusion criteria

Exclusion criteria: 1.A history of allergic reactions to narcotics; 2.The heart, lungs, liver, kidneys and other important organs are severely dysfunctional; 3.There are serious diseases of the central or peripheral nervous system, diseases of the blood system or coagulation dysfunction, and diseases of the endocrine system; 4.Uncontrolled severe hypertension (systolic pressure greater than or equal to 180mmHg, diastolic pressure greater than or equal to 110mmHg) and malignant arrhythmias; 5.The puncture site is infected; 6.History of mental illness, inability to complete VAS and NRS pain scores; 7.Long-term or recent use of opioid sedatives and analgesics; 8.Refuse to use the pain pump;

Design outcomes

Primary

MeasureTime frame
Postoperative pain score;

Secondary

MeasureTime frame
Comfort score;PCA degree;First PCA time;

Countries

China

Contacts

Public ContactLian Xiaoqiang

Second Affiliated Hospital of Guangzhou Medical University

lianxq1987@outlook.com+86 20 3415 2524

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026