Major depressive disorder
Conditions
Interventions
Case group:SSRIs drug therapy
Sponsors
university-town hospital of chongqing medical university
Eligibility
Sex/Gender
All
Age
12 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Must meet the diagnostic criteria for a Major Depressive Episode as outlined in the DSM-5, be experiencing their first episode, and have no history of antidepressant use within the past six months. 2. Must have normal or corrected-to-normal vision, normal hearing, and be right-handed. 3. Must not currently meet the diagnostic criteria for psychiatric disorders such as schizophrenia, bipolar disorder, obsessive-compulsive disorder, or eating disorders.
Exclusion criteria
Exclusion criteria: 1. Pregnant or postpartum women. 2. Current or past history of organic brain diseases (e.g., head trauma, history of seizures). 3. Substance abuse. 4. Severe cardiovascular, hepatic, renal, or endocrine disorders (e.g., thyroid dysfunction). 5.Patients with hematological, autoimmune, or other systemic medical conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression; | — |
Countries
China
Contacts
Public ContactHongzhi Li
university-town hospital of chongqing medical university
Outcome results
None listed