Pneumonia
Conditions
Interventions
group of 3-7years old :Administering propofol combined with remifentanil for general anesthesia in children aged 3-7 who are undergoing bronchoscopy
group of 8-12years old:Administering propofol combined with remifentanil for general anesthesia in children aged 8-12 who are undergoing bronchoscopy
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: (1) Age: 3-12 years old. (2) Gender unrestricted. (3) American Society of Anesthesiologists (ASA) physical status Class I--II. (4) Normal preoperative electrocardiogram and liver and kidney function tests.
Exclusion criteria
Exclusion criteria: (1) Parents of pediatric patients who refuse to participate in the trial. (2) Body weight exceeds the standard weight by more than 20%. (3) History of congenital, hereditary, or psychiatric diseases. (4) History of drug and food allergies. (5) History of surgical trauma and behavioral disorders. (6) History of sedative and analgesic drug use. (7) Significant recent life changes at home (such as death of a family member, moving to a new home, changing kindergartens, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ED50 and ED95 of propofol combined with 2ug/kg remifentanil for bronchoscopy in children aged 3-7 years old;The ED50 and ED95 of propofol combined with 2ug/kg remifentanil for bronchoscopy in children aged 8-12years old; | — |
Secondary
| Measure | Time frame |
|---|---|
| The success rate of general anesthesia induction for bronchoscopy in children aged 3-7 years old using propofol combined with 2ug/kg remifentanil;The success rate of general anesthesia induction for bronchoscopy in children aged 8-12 years old using propofol combined with 2ug/kg remifentanil;Vital signs(SpO2, HR, and MAP) in children aged 3-7 years old during bronchoscopy under the administration of propofol combined with 2ug/kg remifentanil;Vital signs(SpO2, HR, and MAP) in children aged 8-12 years old during bronchoscopy under the administration of propofol combined with 2ug/kg remifentanil;Recovery time in children aged 3-7 years old during bronchoscopy under the administration of propofol combined with 2ug/kg remifentanil;Recovery time in children aged 8-12 years old during bronchoscopy under the administration of propofol combined with 2ug/kg remifentanil; | — |
Countries
China
Contacts
Public ContactZheng Shengxing
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed