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Deopioid analgesia after uvulopalatopharyngoplasty in patients with obstructive sleep apnea - a non-inferior randomized controlled trial

Deopioid analgesia after uvulopalatopharyngoplasty in patients with obstructive sleep apnea - a non-inferior randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101652
Enrollment
Unknown
Registered
2025-04-28
Start date
2025-05-08
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea-hypopnea syndrome, OSAHS

Interventions

Experimental group:Deopioid analgesia
control group:nothing

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-70 years old, gender is not limited; 2. OSA patients who chose UPPP; 3. It is rated I-III by the American Society of Aneshesiologists (ASA); 4. Volunteer to participate in the study and sign an informed consent;

Exclusion criteria

Exclusion criteria: 1. Those with a history of severe heart, lung and other systemic diseases; 2. Patients with severe liver, kidney and blood system dysfunction; 3. A history of gastrointestinal ulcers and drug or alcohol abuse; 4. Patients with a history of mental illness or preoperative cognitive; 5. Patients with a history of allergy to intraoperative drugs;

Design outcomes

Primary

MeasureTime frame
The patient's 24h postoperative pain numerical analogue scale (NRS) score;

Secondary

MeasureTime frame
The incidence of adverse reactions such as respiratory depression, nausea and vomiting, lethargy, dizziness and fever within 48 hours after surgery;The ratio of troponin (CTnI) to troponin (CTnI) 48h after surgery and 24h before surgery;NRS scores were scored 12h, 36h, 48h after surgery;The number and dosage of remedial analgesic drugs during postoperative hospitalization;Incidence of chronic pain three months after surgery;

Countries

China

Contacts

Public ContactShuhai Tang

Qilu Hospital of Shandong University

tangsh@sdu.edu.cn+86 531 82166458

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026