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Perioperative Local Anesthetic Systemic Toxicity-Single center retrospective cross-sectional study

Perioperative Local Anesthetic Systemic Toxicity-Single center retrospective cross-sectional study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101633
Enrollment
Unknown
Registered
2025-04-27
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local Anesthetic Systemic Toxicity

Interventions

Positive group:local anesthetic usage
negative group:local anesthetic usage

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 120 Years

Inclusion criteria

Inclusion criteria: (1) Age: 14 years old or above; (2) Previously received regional anesthesia or pain management in the Department of Anesthesiology of PUMCH; (3) Suspected local anesthetic-related adverse events occurred during the perioperative period.

Exclusion criteria

Exclusion criteria: (1) Incomplete case records or medication data; (2) adverse drug reactions were "probably unrelated" and "unevaluable"; (3) Procedure-related adverse events, such as vascular puncture, hematoma, infection, nerve damage, organ injury, etc

Design outcomes

Primary

MeasureTime frame
Incidence of LAST;

Secondary

MeasureTime frame
Association assessment of LAST related factor;

Countries

China

Contacts

Public ContactJiali Tang

Peking Union Medical College Hospital

tangjiali@pumch.cn+86 18500252430

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026