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A Randomized Controlled Trial Comparing Texture and Color Enhancement Imaging (TXI) Versus High-Definition White Light Colonoscopy for Detecting Colorectal Adenomas in FIT-Positive Patients

A Randomized Controlled Trial Comparing Texture and Color Enhancement Imaging (TXI) Versus High-Definition White Light Colonoscopy for Detecting Colorectal Adenomas in FIT-Positive Patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101610
Enrollment
Unknown
Registered
2025-04-27
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colonoscopy

Interventions

Experimental Group: texture and color enhancement imaging:texture and color enhancement imaging examination
Control Group:High-Definition White Light Colonoscopy:High-Definition White Light Colonoscopy

Sponsors

Beijing Chest Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 74 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1. Consecutive patients aged 40-74 years who were referred to our hospital for screening colonoscopy due to FIT-positive results in a community-based screening program; 2. Signed informed consent.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: 1. Pregnant women, lactating women, or women of childbearing age planning to conceive; 2. Failure to meet screening requirements (e.g., colonoscopy within the past 5 years, personal history of colorectal cancer [CRC] or colorectal adenomas, inflammatory bowel disease, or severe comorbidities); 3. Refusal or inability to undergo polyp resection or biopsy for any reason; 4. Early termination due to patient intolerance of the procedure; 5. Refusal to participate.

Design outcomes

Primary

MeasureTime frame
adenoma detection rate;

Secondary

MeasureTime frame
High-risk adenoma;high-risk serrated lesions;High-risk adenomas per colonoscopy;Serrated lesions per colonoscopy;Insertion time;Withdrawal time;

Countries

China

Contacts

Public ContactLina Feng

Beijing Chest Hospital, Capital Medical University

18844154654@163.com+86 188 4415 4654

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026