Skin barrier
Conditions
Interventions
Experimental group:After taking a proper amount of Runxihe Baby Healthy Skin Plant Extract Shampoo and Bath Bubble, use Runxihe Baby Moisturizing and Soothing Cream as required.
Control Group:After taking a proper amount of Runxihe Baby Healthy Skin Plant Extract Shampoo and Bath Bubble, use Pure Cream as required.
Sponsors
Shanghai Skin Disease Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. the guardian of the volunteer and himself/herself (>=8 years old) volunteers to participate and sign the informed consent form; 2. the volunteer is in good health, currently no skin and systemic diseases affecting the test; 3. there has been dry skin, itchy skin, infantile eczema, diaper dermatitis and other damage to the skin barrier in the past, and the current skin condition is stable, no obvious skin lesions; 4. there is the habit of regular use of moisturizing creams; 5. the guardian of the volunteer or himself/herself ( >= 8 years of age) has a certain expression ability, can truly respond to the subject's feelings after use; 6. the volunteer guardian and himself/herself can strictly comply with the requirements of the study protocol, according to the requirements of the study protocol to assist the subject to use the product and complete the skin test and follow-up; 7. during the trial period does not change the original dietary habits and skin care product use habits, during the trial period does not use supplemental hyaluronic acid-based skin care products.
Exclusion criteria
Exclusion criteria: 1. The volunteers were known to be allergic to the components of the test product; 2. One month before the trial has a sunburn, current or nearly 3 months in any other facial clinical studies or received a dermatologist treatment; 3. Dietary supplements containing collagen, hyaluronic acid, chondroitin sulfate or any combination thereof have been used within 3 months before the trial; 4. Have undergone chemical peeling, botulinum toxin and skin filling treatment within 6 months before the trial; 5. Non-stripping laser within 12 months before the trial; 6. Facial plastic surgery or exfoliative laser within 3 years before the trial; 7. The facial skin is damaged or has skin diseases that affect the observation of facial state; 8. Other unsuitable volunteers: volunteers will also be required to undergo a screening examination in accordance with the requirements of the study protocol, and will be allowed to participate in this study only after their compliance has been confirmed by the study physician; 9. persons who, in the opinion of the investigator, are unsuitable to participate in this clinical trial for a variety of reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss rate, TEWL; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Doctor evaluates the condition of the skin (erythema, scales, dryness);Comparison of local skin images before and after use;Cornemeter skin moisture content;Skin pH value;;Skin oil secretion;Skin microecological parameters;Self-evaluation parameters of volunteers; | — |
Countries
China
Contacts
Public ContactChao Yuan
Shanghai Skin Disease Hospital
Outcome results
None listed