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Efficacy and analysis of vagus nerve magnetic stimulation on cognitive dysfunction after brain injury

Efficacy and analysis of vagus nerve magnetic stimulation on cognitive dysfunction after brain injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101594
Enrollment
Unknown
Registered
2025-04-27
Start date
2023-07-13
Completion date
Unknown
Last updated
2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Treatment group:Repetitive transcranial magnetic stimulation and cognitive training

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.According to the Chinese Guidelines for the Diagnosis and Treatment of Acute Intracerebral Hemorrhage (2019) and the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018), the patient was diagnosed with stroke, and both were confirmed by head CT or MRI scans; 2.The first stroke, the course of which lasted from 1 to 6 months; 3, Right-handed; 4. Age 18-70 years old; 5. Cognitive impairment, Montreal cognitive assessment, MoCA-B score< 26 points; 6. No severe aphasia and able to complete cognitive tests; 7. Stable vital signs without progressive neurological symptoms; 8. Voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Non-first stroke; 2.Complete injury to the left frontal lobe; 3.There are metal implants in the body, cardiac pacemakers cannot be treated with VNMS, etc.; 4.History of brain tumor, traumatic brain injury, epilepsy and risk of seizures; 5.Cognitive decline before stroke; 6.Any neuropsychiatric disorder and obvious affective disorder can affect the test results; 7.Any other factors that affect the assessment and treatment.

Design outcomes

Primary

MeasureTime frame
Functional NIR spectroscopy;

Secondary

MeasureTime frame
Digital Span;Auditory-Verbal Learning ;Montreal Cognitive Assessment;

Countries

China

Contacts

Public ContactZhang Han

Nanchong Central Hospital, Nanchong, China

18281717788@163.com+86 182 8171 7788

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026