None listed
Conditions
Interventions
Non HDL-C elevated group:NA
Non HDL-C normal group:NA
Sponsors
The People’s Hospital of Guangxi Zhuang Autonomous Region
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 40 to 60 years old; 2. Right-handed (referring to someone who is accustomed to using their right hand, also known as right-handed); 3. Exclude any other systemic diseases that can cause brain dysfunction. 4. Those who have not used any lipid-lowering treatment.
Exclusion criteria
Exclusion criteria: 1. Hypertension, diabetes. 2. Dementia. 3. Central nervous system diseases such as cerebrovascular disease, Parkinson's disease, encephalitis, epilepsy, brain tumors, brain trauma, etc. 4. Systemic diseases known to cause cognitive impairment, such as hypothyroidism, VB12 or folate deficiency, neurosyphilis, HIV infection, severe anemia, hepatic encephalopathy, carbon monoxide poisoning, etc . 5. Previous history of mental illness. 6. Material factors such as drug abuse. 7. Contraindications for magnetic resonance imaging examination (such as pacemaker replacement, artificial valve replacement, metal dentures that cannot be removed, uterine contraceptive rings or other metal implants, claustrophobia, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| non HDL-C;Body subcutaneous fat volume, visceral fat volume, body fat percentage, and liver fat content;Rest-MRI;3D T1-Weighted Imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective Cognitive Decline Self Rating Scale (SCD-Q);Pittsburgh Sleep Quality Index (PSQI);Self Rating Depression Scale (SDS);Self Rating Anxiety Scale (SAS);Montreal Cognitive Assessment Basic Scale (MoCA-B) Chinese version;Mini Mental State Assessment Scale (MMSE); | — |
Countries
China
Contacts
Public ContactDemao Deng
The People’s Hospital of Guangxi Zhuang Autonomous Region
Outcome results
None listed